TheDose

Aluminum Starch Octenylsuccinate

Also known as Aluminum starch octenylsuccinate, Starch, hydrogen octenylbutanedioate, aluminum salt, Modified starch aluminum salt

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Aluminum Starch Octenylsuccinate (CAS 9087-61-0) is the aluminum salt of octenylsuccinic acid-modified starch, used as an absorbent, anti-caking agent, and viscosity modifier in cosmetic powders, deodorants, and primers at concentrations up to 30%. The CIR Expert Panel conducted a full safety assessment in 2002 (Nair & Yamarik, IJT 21(S1):1-7, PMID 12042058) covering oral, dermal, ocular, and inhalation toxicity data; no adverse systemic, reproductive, developmental, or sensitization effects were found. The panel determined the ingredient safe as used provided that heavy metal concentration limits applicable to modified food starches are not exceeded. In 2023, the CIR Expert Panel reviewed updated use data and confirmed the ingredient remains acceptable for cosmetic use (Akinsulie et al., IJT 42(3_suppl):12S-13S, PMID 37774506). Consumer concern about systemic aluminum exposure from cosmetics (e.g., antiperspirant/breast cancer hypotheses) is addressed factually by the CIR assessment: the modified starch matrix significantly limits aluminum bioavailability compared to soluble aluminum salts, and the 2002 and 2023 CIR reviews found no evidence of systemic aluminum toxicity from cosmetic use of this ingredient at reported concentrations.


Effective absorbent and anti-caking agent used in face powders, deodorant sticks, pressed powders, and primers to improve texture and reduce caking

Modified starch matrix provides good skin-feel and is derived from a natural polymer base

Inhalation study in rats was negative; minimal dermal irritation and no sensitization found in clinical testing


Concerns

Consumer concern about systemic aluminum exposure: aluminum salts in cosmetics have been the subject of public debate, particularly regarding antiperspirants. The CIR Expert Panel evaluated this ingredient specifically and found no evidence of systemic aluminum toxicity from cosmetic use; the octenylsuccinate-modified starch matrix limits aluminum bioavailability compared to soluble aluminum salts. The SQ finding (safe as used with heavy metal concentration limits) reflects a precautionary impurity control, not a systemic toxicity concern about aluminum itself.

Heavy metal impurity limits: the SQ condition requires that cosmetic-grade material meet established heavy metal concentration limits (equivalent to those for modified food starches), which controls for arsenic, lead, mercury, and cadmium as process-related impurities.


CIR Expert Panel
Approved
safe as used provided that established limitations imposed on heavy metal concentrations are not exceeded
[1]
CIR Expert Panel · Jul 1, 2018Live

CIR Quick Reference Table (12/2017, revised 07/2018) — Aluminum Starch Octenylsuccinate row: Finding=SQ, Detail='safe as used provided th…

Aluminum Starch Octenylsuccinate | SQ | safe as used provided that established limitations imposed on heavy metal concentrations are not exceeded | IJT 21(S1):1-7, 2002QRT-122017revised072018.pdf, p. 5
Verificationpdf_textView source
[2]
Peer-reviewed (PubMed) · Jan 1, 2002

Final report on the safety assessment of aluminum starch octenylsuccinate (Nair B, Yamarik TA; CIR Expert Panel, Int J Toxicol 21(Suppl 1…

Verificationweb_textView on PubMed
[3]
Peer-reviewed (PubMed) · Dec 1, 2023

Aluminum Starch Octenylsuccinate (Akinsulie A et al.; CIR Expert Panel re-review, Int J Toxicol 42(3_suppl):12S-13S, 2023)

Verificationweb_textView on PubMed
[4]
Peer-reviewed (PubMed) · Mar 1, 2018

Safety assessment of starch-based personal care products: Nanocapsules and pickering emulsions (Marto J et al., Toxicol Appl Pharmacol 34…

Verificationweb_textView on PubMed
Sources
4
PubMed citations
3
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.