TheDose

Ammonium Acryloyldimethyltaurate vp Copolymer

Also known as Ammonium acryloyldimethyltaurate/VP copolymer, Aristoflex AVC, Ammonium acryloyldimethyltaurate/vinylpyrrolidone copolymer

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Ammonium Acryloyldimethyltaurate/VP Copolymer is a copolymer of the acrylamide-sulfonic acid monomer acryloyldimethyltaurate (ammonium salt) and vinylpyrrolidone, sold commercially as Aristoflex AVC. The CIR Expert Panel for Cosmetic Ingredient Safety assessed 30 vinylpyrrolidone polymers in 2024 (IJT 43, Suppl. 4) and concluded that 27, including this copolymer, are safe in cosmetics in present practices of use and concentration. The ingredient is used as a rheology modifier and thickener in leave-on and rinse-off formulations at concentrations up to 0.4% in spray products; recent pharmaceutical formulation studies (PMIDs 38831914, 39857623) confirm non-irritating behavior in topical gels at concentrations tested. No ingredient-specific safety concerns beyond residual monomer management (addressed by the CIR panel at the class level) have been identified.


CIR Expert Panel (2024) found Ammonium Acryloyldimethyltaurate/VP Copolymer safe in cosmetics in present practices of use and concentration

Effective rheology modifier and gelling agent for aqueous and oil-in-water systems at low use concentrations (typically 0.4–2%)

Non-irritating in topical formulations; HET-CAM and in vitro studies confirm low irritation potential

High molecular weight synthetic polymer; not expected to penetrate intact skin


Concerns
  • · May release ammonia under alkaline conditions per CIR report chemistry data

Class-level residual monomer concern (acrylamide and vinyl formamide impurities from synthesis) addressed by CIR panel — management via cGMPs expected; no ingredient-specific quantitative data published


CIR Expert Panel
Approved
[1]
CIR Expert Panel · Oct 1, 2024Live

CIR Quick Reference Table (October 2024) — Ammonium Acryloyldimethyltaurate/VP Copolymer row: Finding=S, Citation=IJT 43(Suppl. 4):5-41, …

Ammonium Acryloyldimethyltaurate/VP Copolymer S IJT 43(Suppl. 4):5-41, 2024QRT-Update-100824_0.pdf, p. 16
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[2]
Peer-reviewed (PubMed) · Oct 1, 2024

Safety Assessment of Vinylpyrrolidone Polymers as Used in Cosmetics

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Sources
2
PubMed citations
3
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.