TheDose

Benzyl Alcohol

Also known as Benzyl alcohol, Phenylmethanol, Phenylcarbinol, Alpha-hydroxytoluene, Benzenemethanol

CIREU CosIngPubMed

Safe with conditions

EU CosIng says: restricted.”

Benzyl alcohol is a well-characterized aromatic alcohol used as a preservative, solvent, and fragrance ingredient in cosmetics. The 2017 CIR Expert Panel amended safety assessment (IJT 36(Suppl. 3):5S-30S) concluded that benzyl alcohol, benzoic acid and its salts, and benzyl benzoate 'are safe in the present practices of use and concentration described in this safety assessment,' superseding the 2001 original CIR report. Under EU Regulation 1223/2009, benzyl alcohol is permitted as a preservative at up to 1.0% (Annex V, Entry 34) and is simultaneously listed as a regulated fragrance allergen (Annex III, Entry 45) requiring label declaration when present above 0.001% in leave-on products or 0.01% in rinse-off products. RIFM (2015) assessed it as safe for use as a fragrance ingredient. The dual Annex V/III status is unusual and reflects distinct regulatory pathways: preservative use is concentration-capped; fragrance use triggers disclosure obligations rather than a hard cap.


Broad-spectrum antimicrobial preservative effective against bacteria, yeasts, and molds

Natural occurrence in many essential oils (jasmine, hyacinth) makes it compatible with naturally-derived and fragrance formulations

Functions simultaneously as a solvent, fragrance ingredient, and preservative, allowing formulators to use a single ingredient across multiple roles

2017 CIR Expert Panel confirmed safety under current industry practices and concentrations (unqualified 'S' finding)


Concerns
  • · Regulated EU fragrance allergen (Annex III Entry 45): must be declared on label above 0.001% (leave-on) or 0.01% (rinse-off) due to sensitization potential in susceptible individuals
  • · Mild primary irritant at high concentrations; animal inhalation studies flagged respiratory irritation at high vapor concentrations — relevant for spray-inhalation product categories

Contraindicated for use in medicinal products for neonates and young infants due to risk of metabolic acidosis (noted in EU pharmaceutical guidance; not directly applicable to cosmetics but informs caution in baby-product formulations)


EU CosIng
Restricted — limits vary by context
  • · 1% Annex V Entry 34: max 1.0% as preservative
  • · Annex III Entry 45: fragrance-allergen disclosure required (>0.001% leave-on / >0.01% rinse-off)
CIR Expert Panel
Approved
[1]
CIR Expert Panel · Jul 1, 2018Document match

CIR Quick Reference Table (12/2017, revised 07/2018) — Benzyl Alcohol row: Finding=S (Safe), Citation=IJT 36(Suppl. 3):5-30, 2017; IJT 20…

Benzyl Alcohol | S | | IJT 36(Suppl. 3):5-30, 2017; IJT 20(S3):23-50, 2001 (original report)QRT-122017revised072018.pdf, Benzyl Alcohol row (B section)
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[2]
EU CosIng · Nov 30, 2009Document match

EU Regulation 1223/2009 Annex V (Preservatives) — Entry 34: Benzyl Alcohol, CAS 100-51-6, max concentration 1,0%, no product-type restric…

Entry 34, Benzyl Alcohol, CAS 100-51-6, EC 202-859-9, max concentration 1,0 %EU Reg 1223/2009 Annex V, Entry 34
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[3]
EU CosIng · Nov 30, 2009Document match

EU Regulation 1223/2009 Annex III (Restricted Substances) — Entry 45: Benzyl Alcohol, CAS 100-51-6; fragrance allergen labeling required …

Entry 45, Benzyl Alcohol, CAS 100-51-6, EC 202-859-9; must be indicated in ingredient list per Art 19(1)(g) when concentration exceeds 0,001% in leave-on products or 0,01% in rinse-off productsEU Reg 1223/2009 Annex III, Entry 45
Verificationweb_textView source
[4]
CIR Expert Panel · Jan 1, 2017

Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate (Johnson et al., Int J Toxicol 36(3_suppl):5S-30S, 2…

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[5]
Peer-reviewed (PubMed) · Jan 1, 2001

Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate (Nair B, Int J Toxicol 20(S3):23-50, 2001)

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[6]
Peer-reviewed (PubMed) · Oct 1, 2015

RIFM Fragrance Ingredient Safety Assessment, Benzyl Alcohol, CAS 100-51-6 (Api AM et al., Food Chem Toxicol 84(Suppl):S1, 2015)

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Sources
6
PubMed citations
3
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.