TheDose

Beta-glucan

Also known as Beta-glucan, Oat beta-glucan, Yeast beta-glucan, 1,3/1,4-beta-D-glucan, 1,3/1,6-beta-D-glucan

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Beta-glucan is a well-characterised polysaccharide assessed safe by CIR in the polysaccharide gums group review (IJT 35 Suppl. 1, 2016). Multiple human studies and reviews confirm tolerability and beneficial effects on skin hydration, barrier function, and anti-inflammation. No adverse reactions were reported in clinical trials. Source specificity (oat vs. yeast) affects molecular structure and bioactivity but not cosmetic safety classification; both are covered under the single INCI name and the CIR group assessment.


Skin moisturisation and hydration

Anti-inflammatory and soothing activity

Skin barrier repair

Antioxidant activity

Supports post-procedure skin recovery

UV-protective and erythema-reducing effects


CIR Expert Panel
Approved
[1]
CIR Expert Panel · Jul 1, 2018Live

CIR Quick Reference Table (12/2017, revised 07/2018) — BETA-GLUCAN row: Finding=S, Citation=IJT 35(Suppl. 1):5-49, 2016

Beta-Glucan S IJT 35(Suppl. 1):5-49, 2016QRT-122017revised072018.pdf, p. 12
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[2]
CIR Expert Panel · Sep 1, 2022

CIR Quick Reference Table (September 2022) — BETA-GLUCAN row: Finding=S, Citation=IJT 35(Suppl. 1):5-49, 2016

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[3]
Peer-reviewed (PubMed) · Dec 15, 2023

beta-Glucan extracts as high-value multifunctional ingredients for skin health: A review (Sousa et al., Carbohydr Polym, 2023)

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[4]
Peer-reviewed (PubMed) · Feb 1, 2014

Skin health promotion effects of natural beta-glucan derived from cereals and microorganisms: a review (Du et al., Phytother Res 28(2):15…

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[5]
Peer-reviewed (PubMed) · Jun 1, 2021

Administration of skin care regimens containing beta-glucan for skin recovery after fractional laser therapy: A split-face, double-blinde…

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[6]
Peer-reviewed (PubMed) · Dec 1, 2021

Pleuran-beta-Glucan from Oyster Culinary-Medicinal Mushroom, Pleurotus ostreatus (Agaricomycetes), Soothes and Improves Skin Parameters (…

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Sources
6
PubMed citations
5
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.