TheDose

Cetearyl Glucoside

Also known as Cetearyl glucoside, C16-18 alkyl glucoside, Cetostearyl glucoside

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

The CIR Expert Panel assessed 19 alkyl glucosides as a group, including cetearyl glucoside, and concluded they are safe in the present practices of use and concentration when formulated to be nonirritating (IJT 32(S3):22-48, 2013; PMID 24174472). A 2024 surveillance study (PMID 38575135) confirmed that alkyl glucosides are established contact allergens found in a notable proportion of hypoallergenic rinse-off products, underscoring the SQ finding that irritation avoidance is the key safety condition. The evidence base is moderate: one authoritative group safety assessment and corroborating post-market surveillance.


Nonionic emulsifier derived from fatty alcohols and glucose; considered a natural-origin alternative to ethoxylated emulsifiers

Biodegradable and mild skin profile relative to sulfate-based surfactants

Effective O/W emulsifier enabling stable formulations with light textures


Concerns
  • · Established contact allergen class — alkyl glucosides can cause allergic contact dermatitis in sensitized individuals
  • · Can enhance dermal penetration of co-formulated ingredients; care advised when paired with ingredients whose safety was assessed on low dermal absorption
  • · Found in hypoallergenic products marketed to sensitive skin despite known sensitization potential

CIR Expert Panel
Approved
safe for use in cosmetics when formulated to be non-irritating
[1]
CIR Expert Panel · Jul 1, 2018Archived

CIR Quick Reference Table (12/2017, revised 07/2018) — Cetearyl Glucoside row: Finding=SQ, Citation=IJT 32(S3):22-48, 2013

Cetearyl Glucoside | SQ | safe for use in cosmetics when formulated to be non-irritating | IJT 32 (S3): 22-48, 2013QRT-122017revised072018.pdf, p. 23
Verificationpdf_textView source
[2]
Peer-reviewed (PubMed) · Jan 1, 2013

Safety assessment of decyl glucoside and other alkyl glucosides as used in cosmetics

Verificationweb_textView on PubMed
[3]
Peer-reviewed (PubMed) · Jan 1, 2024

Occurrence of alkyl glucosides in rinse-off cosmetics marketed as hypoallergenic or for sensitive skin

Verificationweb_textView on PubMed
Sources
3
PubMed citations
2
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.