TheDose

Dimethicone

Also known as Polydimethylsiloxane, PDMS, Dimethyl polysiloxane, Silicone oil (dimethyl)

CIR

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Dimethicone (polydimethylsiloxane, PDMS; CAS 9006-65-9) is the most widely used silicone in cosmetic formulations, functioning as a skin conditioning agent, emollient, anti-foaming agent, and film former. The Cosmetic Ingredient Review Expert Panel assessed dimethicone together with the broader family of siloxanes and concluded it is safe as used in cosmetics (published in Int J Toxicol 22(Suppl 2):11-35, 2003). No dermal safety conditions or concentration limits are imposed in the QRT row. Dimethicone is chemically inert, non-reactive with skin components, and does not penetrate intact skin at clinically meaningful levels.


Skin conditioning agent and emollient that imparts a smooth, non-greasy feel

Forms a breathable occlusive film that reduces transepidermal water loss without comedogenicity at typical use levels

Chemically inert and non-reactive with skin components

CIR Expert Panel concluded safe as used in cosmetics:11-35, 2003)


CIR Expert Panel
Approved
[1]
CIR Expert Panel · Jul 1, 2018Live

CIR Quick Reference Table (12/2017, revised 07/2018) - Dimethicone row: Finding 'S' (Safe), Citation 'IJT 22(S2):11-35, 2003'

Dimethicone | S | [no detail column entry] | IJT 22(S2):11-35, 2003QRT-122017revised072018.pdf, p. 44
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Sources
1
PubMed citations
0
Evidence quality
limited
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.