TheDose

Dimethiconol

Also known as Dimethylsilanol, Hydroxy-terminated polydimethylsiloxane, Silicone diol

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Dimethiconol (CAS 70131-67-8) is a hydroxy-terminated polydimethylsiloxane used as a skin and hair conditioning agent and emollient. The CIR Expert Panel completed a dedicated safety assessment in 2017 (IJT 36(Suppl. 3):31-50) covering dimethiconol and its esters and reaction products, concluding these ingredients are safe as used in cosmetics. The Panel cited negligible dermal absorption as the primary rationale for ruling out systemic reproductive, developmental, and carcinogenic risk, consistent with the broader linear silicone safety profile.


Provides skin and hair conditioning; imparts smoothness and slip at typical cosmetic use levels

Hydroxyl end-groups enable reactivity with hair proteins, improving substantivity relative to dimethicone

CIR Expert Panel found safe as used in cosmetics based on negligible percutaneous absorption:31-50, 2017)

Chemically inert polysiloxane backbone; does not react with skin components


CIR Expert Panel
Approved
[1]
CIR Expert Panel · Jul 1, 2018Live

CIR Quick Reference Table (12/2017, revised 07/2018) — Dimethiconol row: Finding=S, Citation=IJT 36(Suppl. 3):31-50, 2017

Dimethiconol | S | | IJT 36(Suppl. 3):31-50, 2017QRT-122017revised072018.pdf, p. 45
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[2]
Peer-reviewed (PubMed) · Nov 1, 2017

Safety Assessment of Dimethiconol and Its Esters and Reaction Products as Used in Cosmetics (Int J Toxicol 36(Suppl. 3):31-50, 2017)

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Sources
2
PubMed citations
1
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.