Ethylhexyl Triazone
Also known as Octyltriazone, Uvinul T 150, Parsol EHT, OT, EHT
“EU CosIng says: restricted.”
Ethylhexyl Triazone (CAS 88122-99-0, Uvinul T 150) is a UVB-absorbing triazine UV filter approved in the EU (Annex VI entry 15) at up to 5%, with no product-type restrictions. The 1997 Scientific Committee on Cosmetology (SCC) opinion (Classification 1, ref XXIV/1376/96) confirmed low dermal absorption by GLP in vitro studies and an appropriate safety margin at 5%; the EU Annex VI approval is the regulatory materialization of that opinion. Ethylhexyl Triazone is NOT approved by the FDA for use in OTC sunscreens in the US (absent from 21 CFR Part 352 monograph) and has no CIR safety assessment (confirmed absent from 12/2017 CIR QRT). In vitro permeation studies (PMID 28216167) confirmed very low systemic absorption under realistic use conditions at 5%. Protein reactivity studies (PMID 25130261) show EHT has the lowest skin protein reactivity among common organic UV filters, suggesting minimal sensitization risk. Photostability studies (PMID 26159738) confirm EHT is photostable under UV exposure.
Excellent UVB-range photostability; photostable under UV exposure, with peak absorption at 314 nm
Lowest protein reactivity of all major organic UV filters tested, suggesting very low skin sensitization risk
Very low dermal penetration confirmed by GLP in vitro studies (SCC 1997 opinion, PMID 28216167); negligible systemic absorption at 5%
EU-approved without product-type restrictions, usable in all leave-on and rinse-off cosmetic formulations up to 5%
Negative for mutagenicity, photomutagenicity, photoclastogenicity, and allergenicity in animal and human testing (SCC 1997)
- · NOT FDA-approved for OTC sunscreen use in the United States (absent from 21 CFR Part 352 monograph); products sold in the US and Canada cannot legally use this ingredient as a sunscreen active
- · CIR has not assessed Ethylhexyl Triazone; confirmed absent from the 12/2017 CIR Quick Reference Table after reviewing all Ethylhexyl entries
sccs coverage_scope dropped: the 1997 SCC opinion page only identifies the ingredient by IUPAC chemical name (2,4,6-Trianilino-(p-carbo-2-ethylhexyl-1-oxi)-1,3,5-triazine), not by INCI name; cannot attach a verifiable excerpt to the sccs regulatory_entry — the EU Annex VI entry materializes the SCC finding and is the verifiable source
EU Regulation 1223/2009 Annex VI — UV filters, entry 15: Ethylhexyl Triazone (2,4,6-Trianilino-(p-carbo-2'-ethylhexyl-1'-oxy)-1,3,5-triaz…
“Ethylhexyl Triazone 88122-99-0 402-070-1 5 %”— EU Regulation 1223/2009 Annex VI, entry 15 (Ethylhexyl Triazone), table row: INCI name, CAS, EC number, maximum concentration