Glyceryl Polyacrylate
Also known as Glyceryl polyacrylate, Ester of glycerin and polyacrylic acid, Glycerol polyacrylate
“CIR Expert Panel says: safe as used in cosmetics.”
Glyceryl Polyacrylate is the ester of glycerin and polyacrylic acid, with a molecular weight greater than 500,000 Da, functioning as a film former and hydrogel-forming humectant in cosmetics. The CIR Expert Panel issued a Final Report in June 2022 concluding all 4 glyceryl acrylates (including Glyceryl Polyacrylate) are safe in cosmetics in the present practices of use and concentration; the QRT records a clean S (Safe) finding with no qualifying conditions. A 2024 multicenter Contact Dermatitis study (n=1,302) found sensitization to the closely related glyceryl acrylate/acrylic acid copolymer is rare. The high molecular weight of Glyceryl Polyacrylate precludes significant dermal absorption, and an Ames test on 1.9% Glyceryl Polyacrylate was non-mutagenic.
Film former and hydrogel matrix that provides sustained moisturization on skin surface
High molecular weight (> 500,000 Da) precludes significant dermal penetration; systemic exposure at cosmetic use levels negligible
Non-mutagenic in Ames test at 1.9% concentration
Non-irritant and non-sensitizer in human repeated insult patch tests at concentrations up to 1.9%
CIR Expert Panel concluded safe in cosmetics in the present practices of use and concentration (Final Report 06/2022)
- · May contain < 5 ppm residual acrylic acid monomer as a process impurity
- · Insufficient safety data for use in airbrush-applied products (data do not support safety via airbrush technology per CIR June 2022 Final Report)
CIR Quick Reference Table (September 2022) — GLYCERYL POLYACRYLATE row: Finding=S, Citation=Final Report Available from CIR 06/2022
“Glyceryl Polyacrylate | S | | Final Report Available from CIR 06/2022”— QuickReferenceTable_AllConclusionTypes.pdf, p. 201