TheDose

Inulin Lauryl Carbamate

Also known as Inutec SL1, Hydrophobically modified inulin (lauryl carbamate), Inulin lauryl carbamate polymer

CIRPubMed

Insufficient data

CIR Expert Panel says: not assessed.”

No ingredient-specific cosmetic safety studies were found on PubMed for Inulin Lauryl Carbamate (CAS 478483-27-1). PMID 26792170 (Muley et al. 2016) studies a related hydrophobically-modified inulin variant (Inutec SP1, stearate/behenate-based) as a drug-delivery micelle carrier for intravenous paclitaxel — this is not a skin safety study and the compound is a different chemical variant. No CIR safety assessment exists for this ingredient (confirmed absent from the CIR QRT as of 07/2018). Overall evidence for cosmetic safety is limited; the ingredient is commercially used as a polymeric emulsion stabilizer/surfactant derived from chicory inulin, and industry safety data (non-CIR) indicates non-irritant, non-mutagenic classification at cosmetic use levels, but no peer-reviewed safety study for this specific ingredient was located.


Polymeric emulsion stabilizer derived from inulin (chicory root), a naturally occurring polysaccharide

Reported 60% lower irritation potential versus conventional surfactants in shower gel formulations

Non-ionic, high-MW polymer — low systemic absorption expected at cosmetic concentrations

Palm oil-free, halal-certified commercial production (Inutec SL1)

Functions as both emulsion stabilizer and surfactant; stabilizes oil droplets and non-water-soluble particles


Concerns
  • · CIR has not assessed this ingredient — no peer-reviewed CIR safety determination
  • · Insufficient published dermal safety data in peer-reviewed literature

Contains alkyl carbamate functionality, which is a structural alert for mutagenicity/carcinogenicity per Benigni/Bossa rules; however, high molecular weight and unfavorable absorption characteristics are expected to preclude membrane permeation and systemic toxicity at cosmetic use levels


CIR Expert Panel
Not assessed
[1]
CIR Expert Panel · Jul 1, 2018

CIR Quick Reference Table (12/2017, revised 07/2018) — INULIN LAURYL CARBAMATE row: absent (no entry found; QRT jumps from 'Inulin' to 'I…

Verificationpdf_textView source
[2]
Peer-reviewed (PubMed) · Mar 16, 2016

Hydrophobically modified inulin as an amphiphilic carbohydrate polymer for micellar delivery of paclitaxel for intravenous route (Muley e…

Verificationweb_textView on PubMed
Sources
2
PubMed citations
1
Evidence quality
limited
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.