TheDose

Passiflora Edulis Seed Oil

Also known as Passion Fruit Seed Oil, Maracuja Oil, Maracuja Seed Oil, Passionflower Seed Oil

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Passiflora Edulis Seed Oil is the cold-pressed oil from the seeds of the passion fruit (Passiflora edulis, Passifloraceae), commonly known as maracuja oil. The lipid profile is dominated by linoleic acid (~70%) with oleic acid (~15%) as the second major component, plus tocopherols and minor polyphenolic constituents — the high linoleic content distinguishes it from oleic-dominant oils like marula or argan. CIR Expert Panel rated Passiflora Edulis Seed Oil S (Safe) under the Plant-Derived Fatty Acid Oils group assessment (IJT 36(Suppl. 3):51-129, 2017). A 2020 dermatology study (PMID 32388391) formulated nanostructured lipid carriers containing the oil and demonstrated non-irritant potential by HET-CAM assay alongside antioxidant activity. A 2021 follow-up (PMID 33713760) confirmed the formulations did not damage human skin cells and showed tyrosinase-inhibitory (depigmenting) activity. A 2022 wound-healing study in rats (PMID 36269233) found that a passion fruit seed oil emulgel reduced inflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and accelerated tissue regeneration.


Very high linoleic acid content (~70%) supports skin barrier function and is well-tolerated by acne-prone skin types (linoleic-rich oils are non-comedogenic)

Lightweight emollient with rapid skin absorption — preferred over oleic-dominant oils for facial formulations

Antioxidant activity from tocopherols and polyphenolic fractions

Demonstrated non-irritant in HET-CAM assay and non-cytotoxic to human skin cells in formulation studies (PMIDs 32388391, 33713760)

Anti-inflammatory effect in animal wound-healing model: reduces pro-inflammatory cytokines and supports collagen formation

CIR-assessed safe under the 244-ingredient Plant-Derived Fatty Acid Oils group:51-129, 2017)


Concerns
  • · As with any plant-derived oil, theoretical risk of contact sensitization in individuals with pre-existing botanical allergies; not commonly reported for passion fruit specifically
  • · Cold-pressed oils may carry trace polyphenols and other unsaponifiables whose composition varies by lot — relevant for marketing claims, not for safety at cosmetic use levels

CIR Expert Panel
Approved
[1]
CIR Expert Panel · Sep 1, 2022Archived

CIR Quick Reference Table (September 2022) — Passiflora Edulis Seed Oil row: Finding=S, Citation=IJT 36(Suppl. 3):51-129, 2017 (Plant-Der…

Passiflora Edulis Seed Oil | S | | IJT 36(Suppl. 3):51-129, 2017QuickReferenceTable_AllConclusionTypes.pdf, p. 319
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[2]
Peer-reviewed (PubMed) · Sep 1, 2020

Lipid nanocarriers containing Passiflora edulis seeds oil intended for skin application

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[3]
Peer-reviewed (PubMed) · May 1, 2021

Design and characterization of Nanostructured lipid carriers (NLC) and Nanostructured lipid carrier-based hydrogels containing Passiflora…

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[4]
Peer-reviewed (PubMed) · Oct 1, 2022

Healing Potential of Propolis Extract-Passiflora edulis Seed Oil Emulgel Against Excisional Wound: Biochemical, Histopathological, and Cy…

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Sources
4
PubMed citations
3
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.