Polyglyceryl-3 Methylglucose Distearate

Also known as Triglycerin methylglucose distearate, Tego Care 450, Polyglyceryl-3 methyl glucose distearate

POLYGLYCERYL-3 METHYLGLUCOSE DISTEARATE (CAS 157175-98-9; C51H98O14; trade name Tego Care 450) is a semi-synthetic polyglyceryl ester emulsifier formed from a polyglyceryl-3 backbone esterified at the methylglucose moiety with two stearic acid chains. It functions as a non-ionic O/W emulsifier and skin conditioning agent, widely used in creams, lotions, and serums. CIR coverage gap: The CIR QRT (12/2017, revised 07/2018) was searched exhaustively. The Polyglyceryl-3 fatty acid esters group assessment (Final report 09/2016; IJT 35 Suppl 3, 2016) covers Polyglyceryl-3 Distearate and related fatty acid esters but does NOT cover the methylglucose ester variant of this backbone. The separate CIR Methyl Glucose Polyethers and Esters assessment (IJT 35(2 suppl):12S-40S, 2016; PMID 27913771) covers 25 methyl glucose esters and polyethers (PEG/PPG variants and simple methyl glucose fatty acid esters) but also does NOT include Polyglyceryl-3 Methylglucose Distearate in its ingredient list. No PubMed studies on this specific ingredient were found. The ingredient is listed in industry databases (SpecialChem, INCIDecoder, CosDNA) as a well-tolerated emulsifier with no known safety concerns, but these are secondary references that do not meet admissibility requirements. No ingredient-specific authoritative source was verified this session.