TheDose

Polyisobutene

Also known as Polyisobutene, PIB, Polyisobutylene

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Polyisobutene is a synthetic hydrocarbon polymer (homopolymer of isobutene) used as a film-former and emollient binder in cosmetics. The CIR Expert Panel conducted a full safety assessment co-covering Polyisobutene and Hydrogenated Polyisobutene (IJT 2008, PMID 19101833): the ingredient is not a dermal irritant, not a sensitizer, not phototoxic, and not carcinogenic in mouse studies. Very limited systemic absorption is expected due to large polymer molecular weight and low water solubility. The 2020 reaffirmation (PMID 32975153) reviewed the polyene group including Polyisobutene and confirmed the original safe conclusion remains in force.


Effective film-forming emollient and binder; used in lip products, mascaras, and skincare at concentrations up to approximately 95% in some lipstick formulations

Not a dermal irritant or sensitizer at cosmetic use concentrations (CIR 2008)

Not phototoxic or photoallergenic — suitable for leave-on sun-exposed formulations

Fully synthetic — no refining-history conditions or PAH contamination risk unlike petrolatum

Not carcinogenic in animal studies; did not promote carcinogenicity of DMBA in mouse studies


Concerns
  • · Non-biodegradable synthetic polymer — environmental persistence concern (not a human safety concern at cosmetic use concentrations)

CIR Expert Panel
Approved
[1]
CIR Expert Panel · Oct 1, 2024Archived

CIR Quick Reference Table (October 2024) — POLYISOBUTENE row: Finding=S, Citation=IJT 27 (Suppl. 4):83-106, 2008; IJT 39(S2):59-90, 2020

Polyisobutene S IJT 27 (Suppl. 4):83-106, 2008;IJT 39(S2):59-90,2020QRT-Update-100824_0.pdf, p. 249
Verificationpdf_textView source
[2]
CIR Expert Panel · Jan 1, 2008

Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as u…

Verificationweb_textView source
[3]
CIR Expert Panel · Sep 1, 2020

Safety Assessment of Polyene Group as Used in Cosmetics — reaffirmation of Polyisobutene and Hydrogenated Polyisobutene (IJT Vol. 39 S2:5…

Verificationweb_textView source
Sources
3
PubMed citations
2
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.