TheDose

Potassium Sorbate

Also known as Potassium sorbate, 2,4-Hexadienoic acid potassium salt, E202, Sorbistat-K

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

Potassium sorbate (CAS 590-00-1; C6H7KO2; potassium salt of sorbic acid) is an EU Annex V-listed preservative (E202) widely used in cosmetics, food, and pharmaceuticals. The CIR Expert Panel assessed sorbic acid and its salts — including potassium sorbate — in 1988 (JACT 7(6):837-80) and reconfirmed the finding in April 2006; the QRT records an unconditional Finding=S with no detail or concentration cap. It is commonly paired with sodium benzoate in 'natural' preservation systems. Literature documents occasional non-immunologic immediate contact reactions (pseudoallergic urticaria-type responses) to sorbic acid at concentrations above 0.1%, distinct from true IgE-mediated allergy; immunologic sensitization (allergic contact dermatitis) is considered rare. Its EU Annex V status (maximum 0.6% as sorbic acid) could not be directly verified via CosIng SPA, so cosing is excluded from coverage scope.


CIR Expert Panel concluded safe as used in cosmetics:837-80, 1988; reconfirmed 04/06) — unconditional Finding=S with no concentration restriction

EU food-additive status (E202) and FDA GRAS (21 CFR 182.3640) for food use supports a long history of safe human exposure via multiple routes

Effective against yeasts, molds, and some bacteria; pairs well with sodium benzoate for broad-spectrum coverage in clean-beauty and 'natural' preservative systems

Markedly water-soluble; compatible with a wide range of cosmetic formulation types

Consumer-facing perception as a 'natural' or 'clean' preservative (derived from sorbic acid, found in nature) makes it popular in brands targeting clean-beauty positioning


Concerns

Non-immunologic immediate contact reactions (pseudoallergic/urticarial) to sorbic acid reported at concentrations above ~0.1%; these are dose-dependent vasodilatory reactions, not true IgE allergy — documented by Ramsing and Menne (1993, PMID 8458215) and historically in Fisher (1980)

pH-dependent activity: potassium sorbate (like sorbic acid) is most effective as a preservative at low to moderately acidic pH (below ~6.5); antimicrobial efficacy decreases substantially in neutral or alkaline formulations

Potential for true allergic contact dermatitis is low but documented in isolated case reports; sorbic acid is not a standard patch test allergen in most screening batteries, suggesting low prevalence in the general population

EU Annex V limits potassium sorbate to a maximum 0.6% as sorbic acid (E202); this cap could not be verified directly via CosIng (SPA barrier) and is excluded from regulatory entries but formulators should apply it when selling in EU


CIR Expert Panel
Approved
[1]
CIR Expert Panel · Jul 1, 2018Document match

CIR Quick Reference Table (12/2017, revised 07/2018) — POTASSIUM SORBATE row: Finding=S (Safe), Detail=blank, Citation=JACT 7(6):837-80, …

Potassium Sorbate | S | [blank detail] | JACT 7(6):837-80, 1988 confirmed 04/06QRT-122017revised072018.pdf, Potassium Sorbate row
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[2]
Peer-reviewed (PubMed) · Feb 1, 1993

Contact sensitivity to sorbic acid (Ramsing DW, Menne T; Contact Dermatitis 28(2):124-125, 1993)

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[3]
Peer-reviewed (PubMed) · Jan 1, 2024

Deciphering trends in replacing preservatives in cosmetics intended for infants and sensitive population (Chen T, Chang H; 2024)

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[4]
Peer-reviewed (PubMed) · Oct 1, 2017

Preservatives in Personal Hygiene and Cosmetic Products, Topical Medications, and Household Cleaners in Spain (Pastor-Nieto MA et al.; Ac…

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Sources
4
PubMed citations
4
Evidence quality
moderate
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.