TheDose

Sclerocarya Birrea Seed Oil

Also known as Marula Oil, Marula Seed Oil

CIRPubMed

Safe

CIR Expert Panel says: safe as used in cosmetics.”

A 2015 randomized controlled trial (n=20, PMID 26528587) found marula oil to be non-irritant on topical application (p<0.001) and demonstrated significant moisturizing, hydrating, and occlusive effects. The oil's fatty acid profile is dominated by oleic acid (~69%), followed by palmitic (~15%) and linoleic (~9%), which are biomimetic to skin lipids. A 2023 NMR-based characterization study (PMID 37515510) established analytical methods for oil authentication and confirmed consistent compositional profiles across geographic sources.


Non-irritant in clinical patch testing at topical use concentrations

Moisturizing and hydrating — statistically significant effect on dry skin

Occlusive effect on normal skin, reducing transepidermal water loss

High oleic acid content (~69%) is biomimetic to skin surface lipids


CIR Expert Panel
Approved
[1]
CIR Expert Panel · Jul 1, 2018Live

CIR Quick Reference Table (12/2017, revised 07/2018) — Sclerocarya Birrea Seed Oil row: Finding=S, Citation=IJT 36(Suppl. 3):51-129, 2017

Sclerocarya Birrea Seed Oil | S | | IJT 36(Suppl. 3):51-129, 2017QRT-122017revised072018.pdf, p. 116
Verificationpdf_textView source
[2]
Peer-reviewed (PubMed) · Jan 1, 2015

Safety and efficacy of Sclerocarya birrea (A.Rich.) Hochst (Marula) oil: A clinical perspective

Verificationweb_textView on PubMed
[3]
Peer-reviewed (PubMed) · Dec 1, 2023

Characterisation of Sclerocarya birrea (marula) seed oil and investigation of the geographical origin by applying similarity calculations…

Verificationweb_textView on PubMed
Sources
3
PubMed citations
2
Evidence quality
limited
Last verified
Re-reviewed when a new CIR / SCCS opinion publishes.